MOLB 7950: Informatics and Statistics for Molecular Biology

This page contains an outline of the topics, content, and assignments for the semester. Note that this schedule will be updated as the semester progresses, with all changes documented here.

MOLB 7950 - {{< var semester >}} Schedule
Classes held in-person in TBD, 9:00-10:30am
Date Block Topic Instructor Title Links
Prepare Slides Exercises HW Key
Week 1
01 Mon, Aug 26, 2024 Bootcamp R Taliaferro Intro to R & RStudio 📖 📄 💪 🧠 .
02 Tue, Aug 27, 2024 Bootcamp R Taliaferro Tidy data & tidyr . . . . .
03 Wed, Aug 28, 2024 Bootcamp R Taliaferro dplyr . . . . .
04 Thu, Aug 29, 2024 Bootcamp R Taliaferro ggplot2 . . . . .
05 Fri, Aug 30, 2024 Bootcamp R Taliaferro ggplot2 . . . . .
Week 2
06 Mon, Sep 2, 2024 - - - NO CLASS: LABOR DAY . . . . .
07 Tue, Sep 3, 2024 Bootcamp R Taliaferro tidyverse odds & ends . . . . .
08 Wed, Sep 4, 2024 Bootcamp R Taliaferro putting it all together . . . . .
09 Thu, Sep 5, 2024 Bootcamp R Taliaferro putting it all together . . . . .
10 Fri, Sep 6, 2024 Bootcamp Statistics Ramachandran Stats intro and history . . . . .
Week 3
11 Mon, Sep 9, 2024 Bootcamp Statistics Ramachandran Probability and descriptive stats . . . . .
12 Tue, Sep 10, 2024 Bootcamp Statistics Ramachandran Hypothesis testing . . . . .
13 Wed, Sep 11, 2024 Bootcamp Statistics Ramachandran Hypothesis testing . . . . .
14 Thu, Sep 12, 2024 Bootcamp Statistics Ramachandran Exploratory data analysis . . . . .
15 Fri, Sep 13, 2024 Bootcamp Statistics Ramachandran Big data concerns . . . . .
Week 4
16 Mon, Sep 16, 2024 DNA Mapping chromatin structure and transactions Ramachandran Experimental overview . . . . .
17 Wed, Sep 18, 2024 DNA Chromatin-centric methods Ramachandran Information from fragment length distributions . . . . .
18 Fri, Sep 20, 2024 DNA Chromatin-centric methods Ramachandran Meta-plots and heatmaps . . . . .
Week 5
19 Mon, Sep 23, 2024 DNA Where do proteins bind in the genome? Ramachandran Experimental overview . . . . .
20 Wed, Sep 25, 2024 DNA Factor-centric methods Ramachandran Peak calling . . . . .
21 Fri, Sep 27, 2024 DNA Factor-centric methods Ramachandran Sequence motif analysis . . . . .
Week 6
22 Mon, Sep 30, 2024 RNA RNA-seq Overview Taliaferro - . . . . .
23 Wed, Oct 2, 2024 RNA Differential Gene Expression Taliaferro - . . . . .
24 Fri, Oct 4, 2024 RNA Differential Gene Expression Taliaferro - . . . . .
Week 7
25 Mon, Oct 7, 2024 RNA Alternative Splicing Taliaferro - . . . . .
26 Wed, Oct 9, 2024 RNA Vignette Taliaferro - . . . . .
27 Fri, Oct 11, 2024 - - - NO CLASS: CSDV RETREAT . . . . .
Week 8
28 Mon, Oct 14, 2024 RNA RBP Taliaferro - . . . . .
29 Wed, Oct 16, 2024 RNA RBP Taliaferro - . . . . .
30 Fri, Oct 18, 2024 RNA Long-read sequencing Hesselberth - . . . . .
Week 9
31 Mon, Oct 21, 2024 RNA Single-cell Riemondy - . . . . .
32 Wed, Oct 23, 2024 RNA Single-cell Riemondy - . . . . .
33 Fri, Oct 25, 2024 - - - NO CLASS: MOLB RETREAT . . . . .
Week 10
34 Mon, Oct 28, 2024 Final - - Final project presentations . . . . .
35 Wed, Oct 30, 2024 Final - - Final project presentations . . . . .